Windows Applications

Network
FileZilla (FTP)
Firefox (web)
FlashGet (download)
Gaim (IM)
NewzCrawler (feed reader)
NewsBin GrabIt (newsgroups)
Thunderbird (email)
mIRC (IRC)

P2P
BitComet (BitTorrent)
eMulePlus (ED2K)
Shareaza (Gnutella)
Soulseek (Soulseek)

Work/Misc
EDXOR (text)
UltraEdit NotePad++ (code)
Adobe Reader (PDF)
Graphpad Prism (graphs/statistics)
Office (writing/spreadsheets unfortunately)
Procite (bibliographies, unfortunately)

Multimedia
AVIcodec (codec information)
BSPlayer (video)
dbPowerAMP Music Converter (convert audio formats)
DigiGuide/WinDAB/WaveFinder (TV/UK digital radio)
DivX Player/Codec (video)
EAC (rip CDs)
ffdshow (directshow video filter)
Gimp (graphics)
Gordian Knot (DVD rip)
Gotcha Covered Pro (album covers)
GSpot (codec information)
IrfanView XnView (images)
Media Player Classic (video)
Mirek's Cellebration (automata)
RealPlayer
Tag&Rename (tag audio files)
UltraFractal
VirtualDub (convert video formats)
Winamp (audio)
XviD (codec)

Music
FL Studio (loop creator)
Acid (track construction)
SoundForge (sound editor)
Reaktor (sound creator)

System
3D Color Changer (colour themes)
AVG (antivirus)
Ethereal (sniffer)
Ad-Aware (adware/spyware)
Nero (burning)
Registry Crawler (search registry)
Sygate Personal Firewall
System Mechanic (system settings)
WinRAR (archives)
98lite (system installation)
X-Setup (system settings)
PrimoPDF (create PDF)
Snadboy's Revelation (reveal passwords)
SnagIt (screen capture)
Tclock2 (customise taskbar)
TransMac (read Mac drives)
FileMon (monitor file access)
RegMon (monitor registry access)
TreeSize (disk usage)