My new favourite method of reading feeds in NetNewsWire is using this stylesheet (a mix of Daring Status Bar and Monochromania), switching to Traditional View, maximising the window and sliding the horizontal and vertical dividers right out to the edge of the window.
This gives an almost fullscreen view - minimizing scrolling - but keeps the toolbar accessible. Pressing the space bar moves through unread items one at a time, always starting at the top of the window so your eyes don't have to search around for them.